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Animal-based studies have shown that the muscles of untrained rats take up as much creatine as the muscles of trained rats,but the ANABOLIC effects of creatine are only obvious in trained rats. So it seems the muscles of untrained rats get the creatine through their skin, but the muscles of trained rats get it through their muscles. In fact if you take creatine after exercise, your muscles get a lot more creatine than they did before, but they also get it through their muscles. This is why a 2g bolus of creatine taken at the end of a workout would give you more muscle than if you took the same amount before and had a rest. It has been observed in several studies that the muscle cells will synthesize far more creatine than they would without it, but will not utilize it completely. So if there's any benefit to creatine after exercise that could make it worth the cost of the supplement, it's this: Your muscles will get a lot MORE creatine in response to your workout than you'd get by using creatine and taking creatine with your usual diet. So if you can afford to wait a while before you get your creatine, it probably wouldn't hurt to do so. Another benefit of creatine after exercise is to help you burn calories. It's been found that you can burn as many as 10-12 kcal/kg (8-12g of energy) per day while on creatine, compared with about 2 kcal/kg (1g of energy) per day before and after workout using natural fat breakdown as an energy source. So if you're in the market for a creatine supplement after exercise, creatine in the form of water and carbohydrates could be a better choice. Another useful study on creatine after exercise found that creatine increased the amount of fat burning that your muscles did before exercise by as much as 30%. If you're going to get creatine anyway, get the water and carbs. For a complete list of creatine ingredients visit Amazon A study found creatine to be equally effective as protein for building muscle, even after 20 minutes of exercise. The benefits of creatine, when taken with exercise seem to be the most apparent as long as it happens after your workout. So the other benefits of creatine are best with your workout, not before it. A study was done on 10 young adults who were randomly divided into 2 groups: (a) a double-blind placebo group that did no exercise; and (b) an exercise and creatine group that did no exercise. The subjects were first given a pre-workout supplement called creatine monohydrate or DM; then the placebo or exercise groups took either creatine monohydrate or Related Article: